Publications

  • Markov Lab

Publications

Publications

  1. Karpova Y., Johnson S.J., Bordet G, Guo D., Ghatak A., Markov D.A., and Tulin A.V. Upregulation of PARG in prostate cancer cells suppresses their malignant behavior and downregulates tumor-promoting genes. Biomedicine & Pharmacotherapy Sept; Vol. 153, 113504. (2022)
  2. Johnson S., Karpova Y., Guo D., Ghatak A., Markov D.A., and Tulin A.V. PARG suppresses tumorigenesis and downregulates genes controlling angiogenesis, inflammatory response, and immune cell recruitment. BMC Cancer. May 18; 22(1): 557. (2022) 
  3. Karpova Y., Guo D., Makhov P., Haines A.M., Markov D.A., Kolenko V., and Tulin A.V. Poly(ADP)-ribosylation inhibition: a promising approach for clear cell renal cell carcinoma therapy. Cancers (Basel) Oct; 13(19): 4973. (2021)
  4. Hillen H.S., Markov D.A., Wojtas D.I., Hofmann K.B., Lidschreiber M., Cowan A.T., Jones J.L., Temiakov D., Cramer P., and Anikin M. The pentatricopeptide repeat protein Rmd9 recognizes the dodecameric element in the 3′-UTRs of yeast mitochondrial mRNAs. PNAS April 13; 118 (15). (2021)
  5. Markov D.A., Wojtas I.D., Tessitore K., Henderson S., and McAllister W.T. Yeast DEAD-box protein Mss116p is a transcription elongation factor that modulates the activity of mitochondrial RNA polymerase. Mol Cell Biol. Jul; 34(13): 2360-9. (2014) 
  6. Markov D.A., Savkina M., Anikin M., Del Campo M., Ecker K., Lambowitz A.M., DeGnore J.P., and McAllister W.T. Identification of proteins associated with the yeast mitochondrial RNA polymerase by tandem affinity purification. Yeast Aug; 26(8): 423-40. (2009)
  7. Markov D., Mosharov E.V., Setlik W., Gershon M.D., Sulzer D. Secretory vesicle rebound hyperacidification and increased quantal size resulting from prolonged methamphetamine exposure. J Neurochem Dec; 107(6): 1709-21. (2008)
  8. Mosharov E.V., Staal R.G., Bove J., Prou D., Hananiya A., Markov D., Poulsen N., Larsen K.E., Moore C.M., Troyer M.D., Edwards R.H., Przedborski S., and Sulzer D. Alpha-synuclein overexpression increases cytosolic catecholamine concentration. J Neurosci, Sep 6; 26(36): 9304-11. (2006) 
  9. King, R.A., Markov, D., Sen, R., Weisberg, R.A., and Severinov, K. A conserved zinc binding domain in the largest subunit of DNA-dependent RNA polymerase modulates intrinsic transcription termination and antitermination but does not stabilize the elongation complex. J Mol Biol, Sept 24; 342(4): 1143-54. (2004)
  10. Markov, D., Christie, G.E., Sauer, B., Calendar, R., Park, T., Young, R.Y., and Severinov, K. P2 growth restriction on an rpoC mutant is suppressed by alleles of the Rz1 homolog lysC. J Bacteriol, July; 186(14), 4628-37. (2004)Gruber, T.M., Markov, D., Sharp, M.M., Young, B.A., Lu, C.Z., Zhong, H.J., Artsimovitch, I., Geszvain, K.M., Arthur, T.M., Burgess, R.R., Landick, R., Severinov, K., and Gross, C.A. Binding of the initiation factor sigma70 to core RNA polymerase is a multi-step process. Mol Cell, July; 8(1): 21-31. (2001)
  11. Gruber, T.M., Markov, D., Sharp, M.M., Young, B.A., Lu, C.Z., Zhong, H.J., Artsimovitch, I., Geszvain, K.M., Arthur, T.M., Burgess, R.R., Landick, R., Severinov, K., and Gross, C.A. Binding of the initiation factor sigma70 to core RNA polymerase is a multi-step process. Mol Cell, July; 8(1): 21-31. (2001)
  12. Markov, D., Naryshkina, T., Mustaev, A., and Severinov, K. A zinc-binding site in the largest subunit of DNA-dependent RNA polymerase is involved in enzyme assembly. Genes Dev, Sept 15; 13(18): 2439-48. (1999)
  13. Nedea, E. C., Markov D., Naryshkina, T., and Severinov, K. Localization of E. coli rpoC mutations that affect RNA polymerase assembly and activity at high temperature. J Bacteriol, Apr; 181(8): 2663-5. (1999)
  14. Severinov, K., Markov, D., Nikiforov, V., Severinova, E., Landick, R., Darst, S. A., and Goldfarb, A. Streptolydigin-resistant mutants in an evolutionary conserved region of the beta' subunit of Escherichia coli RNA polymerase. J Biol Chem, Oct 13; 270(41): 23926-9. (1995)​